xGen Lockdown Panels

DNA probe 사용으로 보관안정성이 높습니다.

각각의 probe를 개별적으로 합성 및 QC하여 probe quality를 높였습니다.

1x tiling density로 probe design 되었습니다.

Hyb time: >4hr

추가 target 디자인이 필요한 경우, 필요한 영역만 추가 디자인 후 기존 panel에 spike-in 가능합니다.

 

xGen Lockdown Panels Target Target size
xGen Exome Research Panel v2 19,433 genes 34 Mb
xGen Acute Myeloid Leukemia Cancer Panel v1.0 >260 genes associated with AML 1.19 Mb
xGen Pan-Cancer Panel v1.5 127 commonly reported mutated gene implicated across 12 tumor tissue type 800 kb
xGen Inherited Diseases Panel genes and SNPs associated with 21 inherited diseases 11.1 Mb
xGen Human ID Research Panel a distinctive set of SNPs, including high minor allele frequency SNPs and a set of 5 gender marker SNPs
xGen Human mtDNA Research Panel human mitochondrial genes 16 kb
xGen CNV Backbone Panel—Tech Access detect copy number variations 0.34 Mb