Singulator 100 System

S2 Genomics의 Singulator 100 system은 single cell research시 가장 까다로운 과정인 tissue dissociation 과정을 cross contamination 걱정 없이 single-use cartridge를 사용해 자동으로 처리해 주는 장비로, fresh tissue (fresh frozen or OCT tissue)를 single-use cartridge에 넣으면 single nuclei 혹은 single cell 을 최소 7분 혹은 protocol 에 따라 1시간 정도면 얻을 수 있습니다.
Downstream으로 10x genomics, BD, Dolomite bio 제품 모두 연결해서 사용하실 수 있습니다.

 

Cells Nuclei
Tissue Type Fresh Fresh, Frozen, OCT
Process Time 20-60 minutes 7 minutes
Yield* 10,000 to > 500,000/mg 20,000 to > 600,000/mg
Viability 70 – 95% N/A
* Varies depending on tissue types

 

현재까지 테스트가 완료된 tissue 종류 (Nuclei)

Type Tissue
Human *Aorta
*Brain (Adult, Infant, Fetal)
*Breast Tumor
*Cerebral Organoids
*Colon (Normal, Polyp & Tumor)
*Heart (Adult & Fetal)
*Hemangioma
*Intestine (Fetal)
*Lung (Fetal)
*Muscle (TA & SA)
*Prostate (Normal & Tumor)
*Retinal organoids (WT & Gene Knockout)
*Spleen (Fetal)
*Thymus (Fetal)
*Vascular Abnormality (Arterial)
*Vascular Abnormality (Lymphatic)
Mouse Brain
Colon (Normal & PDX Tumor)
Heart
Intestine
*Kidney (Normal & Pre-cystic)
Liver
Lung
Lymph
Muscle
Pancreatic PDX Tumor
*Spinal Cord
Spleen
Spiny Mouse (A. cahirinus) *Kidney
Rat Brain
Kidney
Liver
Lung
Spleen
Honeybee (A. mellifera) *Thorax
Arabidopsis *Whole Seedling
*Root Tip
* Customer-Lab Demonstrated

 

Area of Application