NEXTFLEX® Amplicon Panel Kits

100% coverage of exons, flanking intron-exon boundaries, and other regions

High uniformity and on-target reads

Up to 384 unique barcodes allowing for high multiplexing capabilities

Low input requirements for gDNA from fresh or frozen tissues

Simple workflow and < 3 hours hands-on time

Compatible with Illumina and Ion torrent platform

 

Available community amplicon panel

Amplicon Panel Gene Covered
Autism Spectrum Disorders PDE8B, EN2, NLGN4X, CDKL5, NLGN3, MECP2, RPL10
BRCA1/2 XP BRCA1, BRCA2
BRCA1/2 Plus-1 BRCA1, BRCA2, PALB2, CHEK2
CEBPA CEBPA
Colorectal Cancer -1 MLH1, MSH2
Colorectal Cancer-2 MSH6, PMS2
Congenital Adrenal Hyperplasia CYP21A2
Congenital Hyperinsulism ABCC8, GLUD1, KCNJ11, GCK, HADH, HNF4A, INS, INSR, PDX1, SLC16A1 & UCP2
CVD 22 hot spots for cardiovascular disease: MTHFR, F5, AGT, APOB, AGTR1, FGB, F13A1, LTA, SERPINE1, NOS3, JAK2, F2, ITGB3, APOE, PROCR, CBS
Duchenne Muscular Dystrophy DMD
Epilepsy-2 SCN2A, SCN9A
Female Infertility FSHB, FSHR, LHB, LHCGR
HBOC-1 RAD51D, RAD51C, BRIP1
HBOC-2 PALB2, BARD1, TP53
Lysosomal Storage Diseases SUMF1, GLB1, IDUA, ARSB, GUSB, SMPD1, GALC, GALNS, GAA, GLA, IDS
Male Infertility AR, CATSPER1, CFTR, FSHR, LHCGR
Marfan Syndrome FBN1
Mediterranean Fever MEFV
MODY-1 HNF1A, GCK
MODY-2 HNF1B, HNF4A
MODY-3 PDX1, NEUROD1, KLF11, CEL
MODY-4 PAX4, INS, BLK
MODY-5 GCK, HNF1A, HNF1B, HNF4A
Myeloid Selected CDS from 21 genes
Nephrotic Syndrome-1 NPSH1, NPSH2, WT1
Nephrotic Syndrome-2 ARHGDIA, DGKE, LAMB2, PLCE1
Neurofibromatosis NF1, NF2
Neuronal Ceroid Lipofuscinoses CLN3, CLN5, CLN6, CLN8, CTSD, MFSD8, PPT1, TPP1
Obesity-1 LEP, LEPR, POMC, MC4R
Obesity-2 KSR2, SH2B1, SIM1
Periodic Fever-1 TNFRSF1A, NLRP3, MVK
Periodic Fever-2 ELANE, LPIN2, PSTPIP1
Phenylketonuria PAH
TP53 TP53